Doppel-induced cytotoxicity in human neuronal SH-SY5Y cells is antagonized by the prion protein
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منابع مشابه
Doppel-induced cytotoxicity in human neuronal SH-SY5Y cells is antagonized by the prion protein.
Doppel (Dpl) is a prion (PrP)-like protein due to the structural and biochemical similarities; however, the natural functions of Dpl and PrP remain unclear. In this study, a 531-bp human PRND gene sequence encoding Dpl protein was amplified from human peripheral blood leucocytes. Full-length and various truncated human Dpl and PrP proteins were expressed and purified from Escherichia coli. Supp...
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ژورنال
عنوان ژورنال: Acta Biochimica et Biophysica Sinica
سال: 2009
ISSN: 1672-9145,1745-7270
DOI: 10.1093/abbs/gmn005